Protective Role of Interleukin-10 in Atherosclerosis

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Protective role of interleukin-10 in atherosclerosis.

The potential role of anti-inflammatory cytokines in the modulation of the atherosclerotic process remains unknown. Interleukin (IL)-10 has potent deactivating properties in macrophages and T cells and modulates many cellular processes that may interfere with the development and stability of the atherosclerotic plaque. IL-10 is expressed in human atherosclerosis and is associated with decreased...

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The Role of IL-10 in Atherosclerosis

Cardiovascular diseases, including coronary artery disease (CAD), ischemic gangrene, abdominal aortic aneurysms, and many cases of heart failure and stroke currently account for the most number of deaths in the Western world (Hansson et al., 2006). The root cause of these diseases is atherosclerosis, which is widely accepted these days to be a chronic inflammatory disease in addition to the mor...

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ژورنال

عنوان ژورنال: Circulation Research

سال: 1999

ISSN: 0009-7330,1524-4571

DOI: 10.1161/01.res.85.8.e17